Plast Reconstr Surg. 2018 August;142(2) - Chavoin J.P., Taizou M., Moreno B., Leyx P., Grolleau J.L. , Chaput B. This article is based on 25 years of experience and 129 patients with Poland Syndrome treated by 3D custom-made implant. It demonstrates that this technique can achieve high quality aesthetic results (more than 90% of the aesthetic results are considered excellent) and thus respond to the psychological impact of this pathology.
Plast Reconstr Surg. 2016 May;137(5) - Chavoin J.P., Grolleau J.L. , Moreno B., Dahan M., Chaput B. This article is an overview of the experience of 401 cases. It also shows how this technique is the best response to patients' demands (80% of patients were satisfied or very satisfied). The technique is simple and reliable in addition to offering high-quality results. In the short term, this procedure may result render other orthopaedic techniques obsolete, such as the Nuss or Ravitch techniques, which are much more invasive.
Chavoin J.P., Editor © Springer Nature Switzerland AG 2019. It makes original focus as the impact of Pectus and Poland on breasts or the potential respiratory or cardiac disorders associated to the pathology. It also presents alternative surgeries such as remodelling techniques (Nuss or Ravitch), with the risks associated to these last ones. This book demonstrates that in a majority of indications, the technique of custom made implants is the most suitable, providing high quality aesthetic results, while minimizing risks for…
Elsevier - Interest of a 3D custom-made implant in the reconstruction of bone defects of the cranial vault
Annales de Chirurgie Plastique Esthétique 27 July 2023 - Duteille F., Chavoin J.P., Leyx P., Samarut E. A patient was suffering from a severe cranial vault depression following combined neurosurgery and radiotherapy. Due to the aesthetic discomfort and the weakness of the bone flap, it was decided to cover the depression with a 3D custom-made silicone implant.
N Guibert, J Mazières, B Moreno, H Dutau, G Plat, V Héluain, R Kessler, M Porzio - BMJ Journals thorax-2022-219954 - After a tracheal and carinal resection in 2016, the patient developped stenoses of the trachea and bronchus (dyspnoea). Since 2019, 15 stents had to be removed for severe adverse events. Then he was enrolled in the TATUM trial to get a 3D custom-made silicone implant stent. This stent has now been in place for 7 months and the patient reported some dramatic improvements in dypnoea and quality of…
P Roy, V Héluain, P Leyx, T Villeneuve, R Vergé, L Brouchet, N Guibert - ERJ Open Research 2023 9: 00670-2022 - A novel 3D-engineered silicone stent was successfully used to treat a refractory bronchopleural fistula of the right lower lobe in a patient with an open-window thoracostomy who complained of severe dysphonia and recurrent infections.
EMC - ANNPLA-1758; No. of Pages 6 - M. Dupuis, L. Daussy, E. Noel-Savina, M. Dahan, A. Didier, J.P. Chavoin, N. Guibert - This study includes 60 patients with Pectus, who performed pulmonary function tests (PFTs) and exercise capacity (VO2 max) before custom silicone implant correction. It demonstrates that Pectus Excavatum has no impact on respiratory function and exercise capacity in those patients.
Malek MH, Berger DE, Marelich WD, Coburn JW, Beck TW, Housh TJ. - Eur J Cardiothorac Surg. 2006 Oct; 30(4):637–43. - This article examines the effectiveness of the surgical repair of Pectus Excavatum on lung function. Twelve studies have been conducted to address cases of 313 patients with Pectus Excavatum. The results indicate that the surgical repair of Pectus Excavatum does not significantly improve lung function.
The Society of Thoracic Surgeons Published by Elsevier Inc. 2021 - Jean-Pierre Chavoin, MD, PhD, Flavio Facchini, MD, Akshay J. Patel, MA(Cantab), MRCS, and Ian Hunt, MD, FRCS(CTh) - Secondary surgical procedures with a deep customized 3-dimensional elastomer implant are an elegant, effective, and safe solution compared with further corrective revision surgery.
William Hardie & al. - Ventilatory limitations are not associated with dyspnea on exertion or reduced aerobic fitness in Pectus Excavatum - Pediatric Pulmonology 18 June 2021 - Exercice intolerance and chest pain are commun symptoms in PE but in this 259 patients’ study, a pulmonary limitation during exercice was identified in less than 3% of them. Limitations on pulmonary function tests was classified mild in 85% and have poor correlation with the anatomic extent of pectus defect.
Contribution of Three-Dimensional Computer-Aided Design Reconstruction: A Pilot Study - Aesthetic Surgery Journal, 27 June 2020 - Jean-Pierre Chavoin, Elise Lupon, Benjamin Moreno, Pierre Leyx, Jean-Louis Grolleau, Benoit Chaput - Our innovative procedure to correct calf atrophy with custom solid rubber silicone implants produces a calf shape that better adapts to volume loss than prefilled silicone gel implants
Am J Cardiol. 2007 Jun 15; 99(12):1762–4. - Guntheroth WG, Spiers PS. - This article highlights the fact that to date, no research has been carried out that demonstrates that Pectus Excavatum reconstruction operations improve cardiac functions.
Fortmann C., Göen T., Krüger M., Ure B. M., Petersen C., Kübler J. F. - October 12, 2017, Hyun-Sung Lee, Baylor College of Medicine, USA - Comparative study on 20 young patients with unoperated pectus excavatum and 20 others treated by Nuss technique. When metal bars were removed after 3 years, she noticed an abnormally high level of nickel and chromium in blood and urine. Three years after the bars removal, she still finds high levels of these same metal particles.
Cir Esp 2016 Jan;94(1):38-43 - Fibla J.J., Molins L., Moradiellos J., Rodríguez P., Heras F., Canalis E., et al. - Although the Nuss technique revolutionised the surgical treatment of pectus excavatum, its use has not become widespread in Spain. The aim of this study was to analyse the use of this technique between 2001 and 2010 in a sample of Thoracic Surgery Departments in Spain. The risk of complications must be taken into account and its indication must be properly evaluated. 30.6% out of the 149 patients participating in…
J Cardiothorac Vasc Anesth. 2013 Jun; 27(3):436–40 - Umuroglu T, Bostancı K, Thomas DT, Yuksel M, Gogus FY. - The Nuss procedure consists of reconstruction surgery on the chest wall on patients with Pectus Excavatum. Although the Nuss procedure is considered only somewhat invasive, attention must be paid to some of the serious complications associated with surgery and anaesthesia. The complication rate out of the 240 patients studied was 18.7%. Intraoperative hypotension, tachycardia, and hypercapnia are the most common…
Annales de Chirurgie Plastique Esthétique - Volume 64, Issues 5–6, Nov 2019, Pages 620-633 - J.-P. Chavoin, J.-L. Grolleau, B. Chaput, B. Moreno, F. Le Pimpec Barthes, J. Assouad, L. Brouchet, M. Dahan - Pectus Excavatum is the most common malformation of the thorax. Several surgical or medical techniques have been proposed. Some are followed by complications or insufficient results. Secondary surgery with a deep customized 3D implant, may be an elegant and effective solution.
Nicolas Guibert et al. - Treatment of complex airway stenoses using patient-specific 3D-engineered stents: a proof-of-concept study - BMJ Journals Thorax, Volume 74, issue 8 - Anatomically complex airway stenosis (ACAS) represents a challenging situation in which commercially available stents often result in migration or granulation tissue reaction due to poor congruence. A clinical trial of 3D stents has been carried out as a solution for this issue.
Bouchard S, Hong AR, Gilchrist BF, Kuenzler KA. - Semin Pediatr Surg. 2009 May;18(2):66-72. - This paper presents four severe cardiac injuries that occurred in patients who underwent the minimally invasive repair of pectus excavatum (MIRPE). These complications occurred in different clinical settings, namely in a patient with an extremely severe form of pectus, in a patient who had previously undergone an open repair, after a previous open heart surgery, and at the time of bar removal.
Respiratory Medicine, Volume 134, January 2018, Pages 139-142 - Nicolas Guibert, Laurent Mhanna, Alain Didier, Benjamin Moreno, Pierre Leyx, Gavin Plat, Julien Mazieres, Christophe Hermant - New 3D technologies are rapidly entering into the surgical landscape, including in interventional pulmonology. This article focus on the clinical experience in Toulouse which used 3D printing anatomical models of airways to prepare the most delicate interventions.
AJRCCM, Vol. 195, No.7 I Apr 01, 2017 - Guibert N., Didier A., Moreno B., Mhanna L., Brouchet L., Plat G., Hermant C., Mazieres J. - The complex anatomy of some patients with airway pathology excludes the use of conventional stents. A custom-made 3D stent was successfully developed and implanted at the Toulouse University Hospital in a pulmonary transplant patient. The article explains the results, with perfect congruence and immediate improvement of the quality of life of the patient.